Measuring the activity of BioBrick promoters using an in vivo reference standard

Jason R Kelly¹ , Adam J Rubin¹ , Joseph H Davis² , Caroline M Ajo-Franklin³ , John Cumbers⁴ , Michael J Czar⁵ , Kim de Mora⁶ , Aaron L Glieberman⁷ , Dileep D Monie^8,9 and Drew Endy^1,10

¹  Department of Biological Engineering, Massachusetts Institute of Technology, 77 Massachusetts Avenue, 68-580, Cambridge Massachusetts 02139, USA

²  Department of Biology, Massachusetts Institute of Technology, 77 Massachusetts Avenue, Cambridge Massachusetts 02139, USA

³  Molecular Foundry, Lawrence Berkeley National Laboratory, Berkeley, California 94720, USA

⁴  Molecular Biology, Cell Biology, and Biochemistry, Brown University, Box G-W, Providence, Rhode Island, 02912, USA

⁵  Virginia Bioinformatics Institute, Virginia Polytechnic and State University, Washington Street, MC0477, Blacksburg, VA 24061, USA

⁶  Institute for Materials and Processes, The University of Edinburgh, King's Buildings, Mayfield Road, Edinburgh, Scotland EH9 3JL, UK

⁷  Biomedical Engineering, Division of Engineering, Brown University, Providence, Rhode Island 02912, USA

⁸  Department of Ophthalmology, Johns Hopkins University School of Medicine, 600 N Wolfe St, Baltimore, Maryland 21287, USA

⁹  Profectus Biosciences, Inc., 6411 Beckley St, Baltimore, Maryland 21224, USA

¹⁰  Department of Bioengineering, Stanford University, Stanford California 94305 USA