Table 3

Linear dependence of the overall rate of feed-forward motifs on the number of motive nodes
Series
 N
 Iterations range
 Regression
 R2
 SD %
FFA-50
 3–9
 804 – 2160
 219.00 N + 227.14
 0.9796
 4.14
FFB-50
 4–10
 1735 – 3736
 320.18 N + 483.46
 0.9966
 1.43
FFC-50
 4–10
 2043 – 4530
 402.36 N + 481.36
 0.9980
 1.71
FFD-50
 4–10
 1375 – 3428
 329.93 N + 148.50
 0.9939
 2.38
FFE-50
 4–10
 1080 – 2247
 202.93 N + 258.64
 0.9874
 2.62
FFF-50
 4–10
 785 – 1574
 133.36 N + 235.07
 0.9981
 1.70
FFG-50
 4–10
 1955 – 4104
 365.61 N + 395.89
 0.9900
 2.78
FFA-100
 3–9
 2966 – 8444
 920.75 N + 187.50
 0.9996
 0.31
FFB-100
 4–10
 4187 – 9044
 800.93 N + 998.07
 0.9994
 0.29
FFC-100
 4–10
 4542 – 10565
 993.71 N + 556.00
 0.9990
 0.25
FFD-100
 4–10
 3291 – 8067
 802.64 N + 89.357
 0.9993
 0.34
FFE-100
 4–10
 3505 – 7599
 683.57 N + 766.14
 0.9994
 0.33
FFF-100
 4–10
 2408 – 4927
 418.21 N + 705.07
 0.9991
 0.50
FFG-100
 4–10
 2721 – 5086
 397.61 N + 1121.8
 0.9991
 0.42

The overall rate is measured by the number of iterations needed for 50% and 100% conversion of the source substrate into the target product. Seven series (Fig. 3) of feed-forward motifs with different topology, constant number of source cells, N = 500, and constant lattice density, D = 3.6%, are studied.

Apte et al. Journal of Biological Engineering 2008 2:2   doi:10.1186/1754-1611-2-2