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In vivo analysis of fracture toughness of thyroid gland tumors

Nagesh Ragavendra1 email, JW Ju2 email, James W Sayre1,6 email, Sharon Hirschowitz3 email, Inder Chopra4 email and Michael W Yeh5 email

Department of Radiology, The David Geffen School of Medicine at UCLA, Box 957437, 757 Westwood Plaza, Los Angeles, CA 90095, USA

Department of Civil & Environmental Engineering, UCLA, 10833 LeConte Avenue, Los Angeles, CA 90095, USA

Pathology, The David Geffen School of Medicine at UCLA, Box 957437, 757 Westwood Plaza, Los Angeles, CA 90095, USA

Medicine, The David Geffen School of Medicine at UCLA, Box 957437, 757 Westwood Plaza, Los Angeles, CA 90095, USA

Surgery, The David Geffen School of Medicine at UCLA, Box 957437, 757 Westwood Plaza, Los Angeles, CA 90095, USA

Biostatistics The David Geffen School of Medicine at UCLA, Box 957437, 757 Westwood Plaza, Los Angeles, CA 90095, USA

author email corresponding author email

Journal of Biological Engineering 2008, 2:12doi:10.1186/1754-1611-2-12

Published: 6 October 2008

Additional files


Additional file 1:

This movie clip demonstrates the technique of manual probing of the solid thyroid tumor with a fine needle. Note the apparent ease with which the needle travels through a non-cancerous tumor. In contrast, a cancerous tumor offers substantial resistance to needle insertion and penetration. Remarkable differences in haptic force cues were apparent between cancerous and benign tumors.

Format: MOV Size: 7.9MB Download file

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Open Data

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